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lamellar corpuscle
Lamellar corpuscles, or Pacinian corpuscles, are one of the four major types of mechanoreceptor. They are nerve endings in the skin responsible for sensitivity to vibration and pressure. They respond only to sudden disturbances and are especially sensitive to vibration. The vibrational role may be used to detect surface texture, e.g., rough vs. smooth. Lamellar corpuscles are also found in the pancreas, where they detect vibration and possibly very low frequency sounds. Lamellar corpuscles act as very rapidly adapting mechanoreceptors. Groups of corpuscles respond to pressure changes, e.g. on grasping or releasing an object.
==Structure==
Lamellar corpuscles are larger and fewer in number than Meissner's corpuscle, Merkel cells and Ruffini's corpuscles.
The Lamellar corpuscle is approximately oval-cylindrical-shaped and 1 mm in length. The entire corpuscle is wrapped by a layer of connective tissue. Its capsule consists of 20 to 60 concentric lamellae including fibroblasts and fibrous connective tissue (mainly Type IV and Type II collagen network), separated by gelatinous material, more than 92% of which is water. The lamellae are actually very thin, flat, epithelial Cells inside the capsule and modified Schwann cells inside the inner core of the corpuscle. The center of the corpuscle is a neurite of single afferent with oval cross-section and unmyelinated at the receptive region.
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